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There's quite a bit of evidence that populations that live at high altitude (e.g. Sherpa in Nepal) have evolved some physiological changes that allow them to function at high altitude as a non-high altitude adapted person would at sea-level. See this review for one example, but there are many other similar papers and studies. I've been struggling to find ...


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Anecdotally I can tell you in my 20s I was exposed to high altitude 7K feet plus "regularly, maybe two or three times a year. I never suffered any altitude sickness or experienced any shortness of breath. Fast forward to late 30s and beyond I haven't visited high altitude places much and was recently at 10Kfeet altitude and definitely felt it. I don't ...


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